Journal article

Immune biomarkers in the prediction of future myocardial infarctions in people with human immunodeficiency virus

JM Trevillyan, C Moser, JS Currier, T Sallam

Clinical Infectious Diseases | Published : 2020

Abstract

In a retrospective case control analysis, following adjustments for high-sensitivity C-reactive protein (hsCRP), traditional cardiovascular risk factors, and the CD4/CD8 T-cell ratio, higher lipopolysaccharide-binding protein (LBP) was associated with future myocardial infarctions in hsCRP human immunodeficiency virus (HIV). LBP may be a marker of cardiovascular risk with utility in HIV.

University of Melbourne Researchers

Grants

Awarded by National Heart, Lung, and Blood Institute


Funding Acknowledgements

This work was supported by the University of California, Los Angeles Center for AIDS Research (grant number 5P30 AI028697 for administrative support; grant numbers DK118086 and HL139549 for technical staff), the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (award numbers UM1 AI068634, UM1 AI068636, and UM1 AI106701), and the AIDS Clinical Trials Group Specimen Repository Pilot (grant number 116529:1).